Virus Hunter Island Guide


Somewhere in Poptropica, an unknown citizen harbors within his bloodstream a dangerous new virus. Your mission: locate Patient Zero, and eradicate the disease before it spreads. Prepare for a perilous journey to the most far-out place of all — inside the human body!

For walkthroughs on Virus Hunter Island, scroll down.

Released: August 30, 2013 (for members)
or September 26, 2013 (for all)
Common Room: Town Hall
Preceded by: Back Lot Island
Succeeded by: Mocktropica Island

Resources on this page: Island Extras | Synopsis from Poptropica | Video Walkthrough | Written Walkthrough | Album Photos | Trivia

Island Extras: Map | Videos | Official Tour | Nano-Combat Training MiniQuest Guide | Champions Map

Video Walkthrough

For a written walkthrough with pictures, scroll down on this page!

Written Walkthrough

Walkthrough written & pictures taken by Samwow5 (Tough Icicle)
Special thanks to: Strange Cat,Weirdo & Slanted Fish

When you land on Virus Hunter Island, go to the right of Main Street, past the video shop, and into the fitness center. Now, go to the left, past the pool, and click on the stretchy bands next to the weights. One will snap and give you a Resistance Band.


After you get thrown out, go to the bus stop. Climb up onto the nest and use your Resistance Band. Now, climb up and talk to the weird guy.


He says he thinks the government has set up shop where he’s at, and he wants you to go check out one of their vans. Leave the guy and go to the left, past the apartments, and over the brick wall.  Talk to the guy in the “Pizza Delivery Company aka PDC” truck. He’ll run away, and you’ll get a bag of Shredded Documents.


Now, run right and go back to the person on the roof. Piece everything together and go to the video store. Here’s what all of them should look like:


When you finish putting the shreds together, use the PDC ID badge that the guy on the roof gave you.


Enter the video store, show your badge, and go into the Staff Only area. Go down the elevator and talk to the lady with the goggles, Dr. Lange.  Um… what’s wrong with Dr. Lange’s assistant? Is she doing the Gangnam Style? Just kidding – she’s only typing.

Is she doing the Gangnam Sytle?

Anyway, talk to Dr. Lange, who will tell you your badge is a phony, but she wants you to volunteer to help stop the virus. So you say yes, she shows you what the virus can do, and it’s REALLY creepy. She’ll type up a Dossier and also give you a Camera to record Joe Stockman (Patient Zero).


Leave the video store and go into that apartment building again. Rummage through the trash bin, and click on a couple of different letters addressed to “Joe Stockman”.


Head over to the falafel place to the far right, past Main Street. (Go right two streets until you see it at the very end.) The guy there says he’s gotten a huge order for Globochem.

Now go to the Globochem Chemical Lab on Main Street. Run behind him when the panels open and go to the top floor. Talk to Joe and use your camera.


Now go back to Dr. Lange. Follow her, and she will reduce your size so small you’ll be able to fit inside Joe’s body. All in the name of science!


A quick tutorial will show you how to navigate and use the various weapons on your ship, the Panacea. Click on your ship to change your weapon.

  • Laser (red blade): used to cut through things/attack
  • Electrobolt (lightbulb-like): press spacebar to split objects away and clear paths
  • Coagulant (knob-like blob): spacebar to shoot green stuff that will block open areas where blood cells are flowing
  • Gun (has two prongs): spacebar to shoot and attack

After the tutorial, you’ll be ready to enter Joe’s body! Watch as he gulfs down his Chinese food… taking you right along to his stomach.

Now maneuver over to the bottom right of his stomach and shoot at the open area with the coagulant. His ulcer will be cleaned.


Now click a muscle in thin air near it and go to his right arm where it’s infected. Go look for the viruses.


The viruses attack you and take almost all your weapons, except for your gun. We’re going to need to get those weapons back if we want to survive in here!


Go back into the bloodstream, click the stomach (below the heart), and go up the esophagus.


Since it’s too narrow here, you’ll have to get out of the ship and go on foot. Ride these bubbles up to the top and head right.


Keep walking right until you reach a gold tooth at the top. It has your shield on it!


Now, go back to your ship and enter the stomach again. Go all the way down to the bottom left corner and enter the intestines. (You may have to wait a while for the opening to unblock itself.)


Once you reach the intestines, you’ll see a lot of blockage. Go through the intestines, shooting the blockage away by pressing the space bar.


When you reach the end of it, go down… and you’ll come across this big virus! To defeat it, wait for its arms-with-yellow-blobs to come out, then shoot at it by pressing the spacebar. Do this a few times, and the main virus (green part) will be weakened. Shoot at it, and it’ll be gone.


Once you defeat this virus, you’ll get your laser scalpel back, which means you can cut through things!


Go right and cut through some fat/tissue, and you’ll be back in the bloodstream. Click on the heart and cut through some tissue when you get there. You will encounter another virus to fight! Make sure you’re using your laser scalpel, and rush to stab the virus when its “legs” are wide enough for you to go through. Be careful, you’ll lose health if you let the legs touch you. You can regain your health by hitting the blue or red cells.


Keep moving in and out and when you’ve stabbed it enough, it will run off. Follow it and cut through some more tissue, and keep stabbing it. After a certain amount of hits, the virus runs off again. Follow it again, cut through the tissue, and keep stabbing him. It’ll run off a final time – keep stabbing, and it’ll be gone. You’ll get your coagulant back!


Now, go back into the bloodstream and visit Joe’s right hand. Use your coagulant to seal up all the tissue hemorrhages.


After you do that, go back into the bloodstream. Go into the right arm and shoot at all the tissue cuts with the coagulant. When you finish all of them, go right at the end.


Some viruses will come after you, and you’ll need to fight them off and continue sealing up tissues with the coagulant. The viruses care about hurting the tissues more than hurting you, so shoot the tissues until they turn green, then shoot the sacs where the viruses come from (there’s two). You can use either the laser scalpel or gun to attack.


When you finish shooting the sacs, kill the remaining viruses that are trying to hurt you. Then shoot all the sacs again, and you will retrieve your electrobolt.


Once you get the Electrobolt, shoot the blue nerves while you’re leaving. It relieves Joe (Patient Zero) of his pain. Now go back into the bloodstream.


From there, go to the brain. When you get there, use your Electrobolt to get rid of the blue nerve. You’ll see this beastly virus that looks like it came out of a horror film.


Now here’s the tricky part. Your weapons don’t hurt the big virus. (However, you can defeat the little viruses it sends in your direction with your laser scalpel.)

Go left and use the Electrobolt (remember to press the space bar) with the blinking neuron. After it lets go, it will follow you. Connect it to the next one and so on until it reaches the virus and shocks it. Each time the big virus is shocked, it will move to a different area, and you’ll need to keep connecting the blinking neuron to the neuron the big virus is sitting on.)

Shock him 5 times and you’ll get the Gravity back. Now, use the Coagulant and shoot the tissues. After that, go back into the bloodstream, and into the mouth.


Once you’re inside the mouth, go down under the bottom teeth. You will reach the cavity. Keep poking it with your laser scalpel and the cavity will go away.


After you do that, go into the bloodstream again, and return to the heart. Use your electrobolt and press spacebar on the blue nerves to ease the muscles out of the way, and keep going until you reach the end. Enter the last area – the lungs.

When you get inside the lungs, another virus will be waiting. To defeat this one, keep hitting its arm while it’s on the alveolar sacs. The arms will eventually fall off, and the virus will be contained.


Joe will then sneeze you out, and you’ll get your island medallion from Dr. Lange! Congratulations – you’ve completed Virus Hunter Island!

Bonus Quest (members only)

Go to the Knave’s landing. A dog will run away from its owner. The owner will say that her dog, Belle, has been acting strange ever since she ate rubbish from the trash. She’ll ask you to help her dog, and you will get what she ate out of – it’s something with the PDC’s initials on it!

Go to the PDC lab and talk to Dr. Lange. She’ll tell you about why the dog has been acting in a frenzy. It seems as if she ate the PDC’s heartworms, which were thrown away! (Ugh,not again!)

So you get out and go to the falafel place.The guy will give you some leftovers. Feed them to Belle, and you’ll be in the dog’s body. Now, near her upper canine teeth, there’ll be some wounds. Cure them with your curing thingy. Go right. There will be two green long swiping things, probably a result of the heartworms. Speaking of the very devil, the heartworms are blocking a tunnel down right.

You will have to hit the thingies first with your gun to make them disappear, then the heartworms will go. But not all of them! Continue right through a tunnel to a stomach. Use the laser to go through the fat, and go through the ‘Pop Chow’ by shooting it with your gun. Soon you’ll reach a tunnel for the intestines. Go through it.

You will be in a maze of nerves. There will be nerves of different colors which will open paths with the door of their same color, but may close another one with the same color. Go through that and experiment with it. Kill all the green swinging things with your gun. After you reach a dead end, go back through it and exit. Then go and exit the stomach.

Then the heartworms will stop blocking the passage, and you can go into the lungs (yes, already). There will be smaller lungs with—YA!!!! GREEN SWINGING THINGS EVERYWHERE!! THEY MOVE THEMSELVES FROM ONE HOLE TO ANOTHER!!! YOU’VE GOTTA STOP ‘EM!

So you shall have to shoot at them from near their holes. They may escape from one hole to another, but then just switch holes! After you shoot all of them, a small tunnel will open up. Go through it for the final final battle, this time in the heart. When you enter, you’ll meet the center of the heartworm. Shoot at its four parts till it sprouts.

Shoot at the sprouts from a safe distance. Then the white cells will finish it off! The heartworm is contained! A blue tunnel will open up which will take you back to the mouth. Then, exit the mouth, and you’ll arrive back safely on Main Street. The girl will thank you, and Dr. Lange will reward you with the Ace Pilot costume. Congrats, you’re done!

Looking for more walkthroughs? Check out our Island Help page! 🙂

Album Photos

These pictures appeared in a former feature known as the photo album.


  • Virus Hunter Island is Poptropica’s 35th island. It was released on August 30, 2013 for members with a demo for non-members, and everyone could get a free Hazmat Suit on Main Street. The login screen featured two viruses chasing the kids that usually run across the screen, then someone in the round body-travel vehicle shooting them away. It will be released to everyone on September 26, 2013.
  • Virus Hunter Island was re-released for Steam on May 25, 2022.
  • The name of the island was discovered through a post on the blog of Poptropica artist Nasan Hardcastle, where he showed images of characters he designed for Poptropica, including the unreleased anatomy-themed “Virus Hunter” island. The island was confirmed by Poptropica on May 15, 2013.
  • Common room: Town Hall
  • This is the first island to be released with music and bigger navigation (excluding 24 Carrot BETA Carrotene, which was the first to be upgraded from its lesser version).
  • There is a letter in the trash for a “Nasan SoftFort,” a pun on Nasan Hardcastle’s name.
  • This is the first island to have a world champions player map which shows the rankings for finishing the island.
  • There is a poster on the outside of the GreenSquare video store for Revenge of the Zombie Carrots, which is the sequel of the Zombie Carrot movie shown on Zomberry Island.
  • Waist Not Fitness Center has a logo similar to The Biggest Loser.
  • In the fitness center, you can open the lockers without locks. (One has a picture of a dog!)
  • Bucky Lucas of Reality TV Island is frequently referenced throughout the island, including when you trick Joe into taking his picture.
  • There are computers in Globochem on websites Funbrain, Fact Monster, and even what appears to be Poptropica. Also, there’s a screen on what looks like Facebook as well as a game of Solitaire.
  • In GreenSquare, the cardboard cutout for a movie called ‘Stuck in Detention’ is a reference to the 1985 movie The Breakfast Club, and the boy shown parodies the character John Bender.
  • GreenSquare is a parody of the DVD rental company Redbox.
  • The plot of Virus Hunter Island may have been inspired by the 1987 science fiction movie Innerspace.
  • My Boyfriend is a Martian is a reference to the TV series My Babysitter’s a Vampire.
  • The gag with the “Pizza Delivery Company” van being a cover for the PDC was directly ripped off from a joke on the Simpsons. There’s a truck parked outside the Simpson’s house called “Flowers By Irene” that has FBI agents inside, and the second Marge notices it, the van takes off and is replaced by one that says “Pizza Delivery” with police officers inside.
  • The name of the company that Joe works for, GloboChem, was a reference to a joke on the TV show Mr. Show.
  • Virus Hunter was the culmination of Pop Creator Mitch Krpata‘s years-long quest to make a Super Metroid-style adventure on Poptropica. He says, “It didn’t go well, and I apologize.”
  • During Early Access, there was a vending machine on Main Street where you can come back every week to collect a new free prize. When a new prize was released, the previous ones would be ‘Sold Out.’ The prizes so far were a Hazmat Suit and Scifi Doctor costume, available to everyone. The next prize (a helmet) will be for members only (available Sept 12). On Sept 19, a final mystery prize will be available to everyone.
  • Bonus quest: Poptropicans are feeling fine, but man’s best friend isn’t so lucky. Now, a sick dog needs your help. Head back into the fray to take down a new threat: the vicious heartworm!
  • Previously, members would get an additional Virus Hunter Island gear pack, which includes Virtual Virus costume, Inside-Out power, and Sneezing Powder item. The Virtual Virus costume was only available during Early Access.
  • Members could also play a Nano-Combat Training Game to prepare for Virus Hunter, which was available in the Store.

an apple a day keeps the doctor away


304 thoughts on “Virus Hunter Island Guide”

    1. I am late, aren’t I?
      In the brain, my shocker thingy was shocking every. Freaking. Time. It wouldn’t stop, and it was so hard to shock the stupid virus.

  1. I can’t put the Shredded Documents together because I can’t drag them! What should I do? Please help me! Thanks in advance!

      1. What was the solution to the problem because the same thing happened to me and it still won’t work

  2. This question is for those who know about old videogames:
    Has anyone realized that, from a certain point, this island looks like the Metroid Fusion videogame?

  3. I am stuck at the part where it says “Unstable air currents. Can not proceed without gravity core.” Please help

  4. I am stuck in the heart! I can’t defeat the virus and don’t know what cells are supposed to give me energy!

  5. Honestly this game is very annoying! I beat the brain virus thing but when I go on the map of his body the mouth isn’t there! I tried skipping it but when I go to where the final boss is it says the no gravity thing and you can’t move. Does anyone know how to reset this specific island while in the body? I’m deciding to start over.

  6. This tutorial is ok but written badly and hard to follow. How do you beat the first virus attack?

    Slanted Fish: The walkthrough does say to press spacebar to shoot. 😛

  7. when i was in the brain, i killed the virus but it wouldnt let me leave because the muscles were expanded and i tried signing out and back in and it doesnt work

  8. Great walkthrough, but try to be more specific, I was confused on the Boss Virus. You said to POKE it but you had to shoot the Boss Virus. Other than that it was a good walkthrough. 😀

  9. pizza guy ain’t there. I think it’s a glitch. i tried to use my cell phone from nabooti to call him, but the island’s under construction so… can’t do that!

    Slanted Fish: Pizza guy is in a truck in Knave’s Landing, all the way left. Items from other islands aren’t going to help…

  10. I got a glitch. I was in his mouth and then I pushed a button and then i fell into a gap in his teeth and now I can’t get up 😦

  11. Although I finished beating the boss in the brain, it never showed that I got the gravity back. I saw the white blood cells and even filled in the cut, but there was a bug and I don’t have access to the mouth still. What do I do?

  12. I cant join the wire thingies in the brain.If i do it then the big virus’s little virus come and destroys my ship.HELP ME STAFF!

  13. I found out that in the fitness center, if you were holding the barbells, click on someone to talk to them and you will keep holding the barbells!

  14. i didnt really get any intressed in that island but i guess it was okay could have been better i really loved the mystery train though that one was the bomb

  15. I tried attacking the last virus and it wont do anything. I even tried all the weapons and tried electrocuting it. what do I do? HELP!

  16. My nerve thing wont budge and i think there is a bug because it won’t
    let me leave if some one could help plz do!

    1. Ayup. I’m the one who wrote the walkthrough for the Bonus Quest,actually. Looking back,I find it hilariously how…strangely unedited it is. Surprised after all this time it hasn’t been renovated,actually,

    1. Are you on Chrome? Chrome is NAUSEATING on Chrome! (THIS MEANS HORRID) Try internet explorer and if that doesn’t work, try Mozila Firefox. 😉 ;(
      Blue. XxX

  17. So… I’m stuck right after you complete the tutorial, where the loading screen is supposed to be all there is is a black screen and the steering thingy…


      1. Don’t worry- I’ve got it. Go left from Main Street and it’s the one with Knaves Landing I think it was with the crown logo.
        🙂 Blue

      2. I’ve always wanted to do walkthroughs! But somehow, they always fail even if I’m a master at it!!! 😦
        P.S. Slanted Fish, U R my favourite Poptropican!!!

  18. When will Realms be open again? I never see information that’s up-to-date. I don’t think it would take almost 3 years now to fix an error or two with it. Please tell me something, I really love Poptropica Realms and I want to see it again.

    1. We don’t know when, if ever, Realms will return. Poptropica Original is not a priority for the Creators right now, considering that the old technology it runs on (Flash) will be retired by the end of 2020. That’s why they’re focusing on Worlds, which is built with a newer technology, and also comes with a building feature in the form of player homes (albeit not the same thing as Realms). To get the latest news on what’s going on in Poptropica, check in on our blog.

  19. I’d like to mention that the heart arrhythmia in Joe’s heart is never mentioned in the walkthrough. I’m unsure if it’s required to complete the island, but it’s an easy fix. Using the electrobolt on the irregularly fast nerve endings will solve the issue.

  20. Also, as I just realized, the blockage caused by the penny in the intestines isn’t mentioned either. In addition, the tissue calcification in Joe’s right arm isn’t included (those rocks that gathered in Joe’s arm, which were causing his pain.)

    Virus holds gun at me.
    I am dead

  22. After the tutorial on the ship’s controls, I am met with a perpetual black loading screen. I don’t know how to get around it – any attempt to refresh or leave the island and return results in having to do the tutorial again. It’s one of the last islands I have left unfinished.

  23. Joe won’t appear even though I’ve dug through the trash so many times it won’t let me click it anymore. I’ve reloaded and everything but it still won’t work. Any quick fixes?

  24. I can’t get past the big virus in the brain. The little viruses keep coming and they stop me from getting to the chains 😦


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